antagonist, also active as 5-HT1
antagonist. Differentiates 5-HT1D
sub-types. Also displays affinity for rodent 5-HT5B
values are 6.6, 7.0, 8.4 and 8.7 respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Metitepine distinguishes two receptors mediating inhibition of [3H]-5-hydroxytryptamine release in guinea pig hippocampus.
Wilkinson and Middlemiss
Naunyn Schmiedebergs Arch.Pharmacol., 1992;345:696
The peripheral actions of 5-HT.
Ed. Fozard. Oxford., 1989;
The citations listed below are publications that use Tocris products. Selected citations for Methiothepin maleate include:
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