Methiothepin maleate

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Metitepine distinguishes two receptors mediating inhibition of [³H]-5-hydroxytryptamine release in guinea pig hippocampus.
   Wilkinson and Middlemiss
   Naunyn Schmiedebergs Arch.Pharmacol., 1992;345:696
3. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).
   Hoyer et al.
   Pharmacol.Rev., 1994;46:157
4. In the search for selective ligands of 5-HT₅, 5-HT₆ and 5-HT₇ serotonin receptors.
   Wesołowska et al.
   Pol.J.Pharmacol., 2002;154:327
5. Higher-end serotonin receptors: 5-HT₅, 5-HT₆, and 5-HT₇.
   Glenon et al.
   J.Med.Chem., 2003;46:2795

Product Datasheets