MGC20410 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-38963

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all MGC20410 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MHLCGGNGLLTQTDPKEQQRQLKKQKNRAAA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MGC20410 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MGC20410 Antibody [NBP2-38963]

Immunocytochemistry/ Immunofluorescence: MGC20410 Antibody [NBP2-38963]

Immunocytochemistry/Immunofluorescence: MGC20410 Antibody [NBP2-38963] - Staining of human testis shows strong positivity in nucleoli in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963] - Staining of human kidney shows strong positivity in nucleoli in cells in tubules.
Immunocytochemistry/ Immunofluorescence: MGC20410 Antibody [NBP2-38963]

Immunocytochemistry/ Immunofluorescence: MGC20410 Antibody [NBP2-38963]

Immunocytochemistry/Immunofluorescence: MGC20410 Antibody [NBP2-38963] - Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoli.
Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963] - Staining of human colon shows nucleoli positivity in glandular cells.
Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963] - Staining of human colon shows strong positivity in nucleoli in glandular cells.
Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963]

Immunohistochemistry-Paraffin: MGC20410 Antibody [NBP2-38963] - Staining of human Fallopian tube shows strong positivity in nucleoli in glandular cells.

Applications for MGC20410 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MGC20410

BATF2 (Basic leucine zipper transcriptional factor ATF-like 2) is a 274 amino acid member of the AP-1 transcription factor family. It controls the differentiation of lineage-specific cells in the immune system. It participates in differentiating CD8+ thymic conventional dendritic cells and acts by forming a heterodimer with JUN family proteins. They then recognize and bind the DNA sequence 5'-TGA(CG)TCA-3'. It acts as a tumor suppressor by interfering with AP-1 regulated activation of CYR61/CCN1 transcription and its downstream signaling. CYR61/CCN1 signaling induces anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma.

Alternate Names

basic leucine zipper transcription factor, ATF-like 2, basic leucine zipper transcriptional factor ATF-like 2, B-ATF-2, MGC20410, SARI, suppressor of AP-1 regulated by IFN

Gene Symbol

BATF2

UniProt

Q8N1L9 (Human)

Additional MGC20410 Products

Product Documents for MGC20410 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for MGC20410 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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