Mind Bomb 1/MIB1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-81754

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Mind Bomb 1/MIB1 Primary Antibodies »

Product Specifications

Immunogen

MIB1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human MIB1. The immunogen is located within amino acids 920 - 970 of MIB1.

Specificity

Mind Bomb 1/MIB1 antibody is human, mouse and rat reactive. At least three isoforms of Mind Bomb 1/MIB1 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

103 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Mind Bomb 1/MIB1 Antibody - BSA Free

Western Blot: Mind Bomb 1/MIB1 AntibodyBSA Free [NBP2-81754]

Western Blot: Mind Bomb 1/MIB1 AntibodyBSA Free [NBP2-81754]

Western Blot: Mind Bomb 1/MIB1 Antibody [NBP2-81754] - Analysis of Mind Bomb 1/MIB1in A431 cell lysate with Mind Bomb 1/MIB1 antibody at 1 ug/ml.
Immunocytochemistry/ Immunofluorescence: Mind Bomb 1/MIB1 Antibody - BSA Free [NBP2-81754]

Immunocytochemistry/ Immunofluorescence: Mind Bomb 1/MIB1 Antibody - BSA Free [NBP2-81754]

Immunocytochemistry/Immunofluorescence: Mind Bomb 1/MIB1 Antibody [NBP2-81754] - Immunocytochemistry of Mind Bomb 1/MIB1 in A431 cells with Mind Bomb 1/MIB1 antibody at 5 ug/mL.
Mind Bomb 1/MIB1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Mind Bomb 1/MIB1 Antibody - BSA Free [NBP2-81754] -

Immunocytochemistry/ Immunofluorescence: Mind Bomb 1/MIB1 Antibody - BSA Free [NBP2-81754] - Immunofluorescence of Mind Bomb 1/MIB1 in A431 cells with Mind Bomb 1/MIB1 antibody at 20 ug/mL.

Applications for Mind Bomb 1/MIB1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Mind Bomb 1/MIB1

E3 ubiquitin ligase protein mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. It positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.

Long Name

Mindbomb Homolog 1

Alternate Names

DIP1, MIB1, ZZANK2

Gene Symbol

MIB1

Additional Mind Bomb 1/MIB1 Products

Product Documents for Mind Bomb 1/MIB1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Mind Bomb 1/MIB1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail