Catalog Number: 4104
Chemical Name: (3aS,4S,6aR)-Hexahydro-2-oxo-N-[2-[2-[2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]ethoxy]ethoxy]ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide
Biological Activity
Biotinylated anandamide analog; acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide. Blocks anandamide uptake (IC50 = 0.5 μM in HaCaT cells); prevents interaction with FAAH, CB1 and TRPV1.
Technical Data
  • M.Wt:
    660.95
  • Formula:
    C36H60N4O5S
  • Solubility:
    Soluble to 100 mM in DMSO and to 50 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    956605-71-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under licence from the University of Rome and the University of Teramo
Background References
  1. Pitfalls and solutions in assaying anandamide transport in cells.
    Oddi et al.
    J.Lipid.Res., 2010;51:2435
  2. Characterization of biotin-anandamide, a novel tool for the visualization of anandamide accumulation.
    Fezza et al.
    J.Lipid.Res., 2008;49:1216
  3. Evidence for the intracellular accumulation of anandamide in adiposomes.
    Oddi et al.
    Cell Mol.Life Sci., 2008;65:840
  4. Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins.
    Oddi et al.
    Chem.Biol., 2009;16:624

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