MMP-8 Antibody

Novus Biologicals | Catalog # NBP2-17316

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all MMP-8 Primary Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human MMP-8. The exact sequence is proprietary.

Localization

Cytoplasmic granule; Secreted; extracellular space; extracellular matrix (Probable)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MMP-8 Antibody

Western Blot: MMP-8 Antibody [NBP2-17316]

Western Blot: MMP-8 Antibody [NBP2-17316]

Western Blot: MMP8 Antibody [NBP2-17316] - Sample (30 ug of whole cell lysate) A: HCT116 7. 5% SDS PAGE gel, diluted at 1:10000.
Immunocytochemistry/ Immunofluorescence: MMP-8 Antibody [NBP2-17316]

Immunocytochemistry/ Immunofluorescence: MMP-8 Antibody [NBP2-17316]

Immunocytochemistry/Immunofluorescence: MMP8 Antibody [NBP2-17316] - Immunofluorescence analysis of methanol-fixed A431, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: MMP-8 Antibody [NBP2-17316]

Immunohistochemistry-Paraffin: MMP-8 Antibody [NBP2-17316]

Immunohistochemistry-Paraffin: MMP8 Antibody [NBP2-17316] - Immunohistochemical analysis of paraffin-embedded Hepatoma, using antibody at 1:500 dilution.
Immunoprecipitation: MMP-8 Antibody [NBP2-17316]

Immunoprecipitation: MMP-8 Antibody [NBP2-17316]

Immunoprecipitation: MMP-8 Antibody [NBP2-17316] - IP samples: A549 whole cell extract A. Control with 4 ug of preimmune Rabbit IgG B. Immunoprecipitation of MMP8 protein by 4 ug MMP8 antibody 10 % SDS-PAGE The immunoprecipitated MMP8 protein was detected by MMP8 antibody diluted at 1:500. [EasyBlot anti-rabbit IgG was used as a secondary reagent]

Applications for MMP-8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Immunoprecipitation

1:100-1:500

Western Blot

1:5000-1:20000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: MMP-8

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]

Long Name

Matrix Metalloproteinase 8

Alternate Names

Collagenase 2, MMP8

Gene Symbol

MMP8

UniProt

P22894 (Human)

Additional MMP-8 Products

Product Documents for MMP-8 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for MMP-8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

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