2B4, also known as CD244, is a cell surface glycoprotein belonging to the CD2 subgroup of the immunoglobulin superfamily. It acts as a high-affinity receptor for CD48. It is expressed by natural killer (NK) cells and CD8+ T cell subsets. It can regulate killing by CD8+ T cells and NK cells, and IFN-gamma secretion by NK cells. It may also regulate NK cell and T cell proliferation.
Mouse 2B4/CD244/SLAMF4 (NP_061199) VersaClone cDNA
R&D Systems | Catalog # RDC2711
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Background: 2B4/CD244/SLAMF4
Alternate Names
CD244, NAIL, NKR2B4, Nmrk, SLAMF4
Gene Symbol
CD244
UniProt
Additional 2B4/CD244/SLAMF4 Products
Product Documents for Mouse 2B4/CD244/SLAMF4 (NP_061199) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse 2B4/CD244/SLAMF4 (NP_061199) VersaClone cDNA
For research use only
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