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Mouse Bax MAb (Clone YTH-5B7)

Catalog #: 2280-MC
2 Citations Datasheet / COA / SDS

Discontinued Product

2280-MC has been discontinued.
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Citations (2)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Bax MAb (Clone YTH-5B7) Summary

Species Reactivity
Mouse
Source
Monoclonal Mouse IgG1 Clone # YTH-5B7
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
Please refer to the PDF datasheet for specifications.
Immunoprecipitation
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Bax

B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.

Long Name
Bcl Associated X Protein
Entrez Gene IDs
581 (Human); 12028 (Mouse); 24887 (Rat)
Alternate Names
apoptosis regulator BAX; Bax; BCL2-associated X protein; Bcl2-L-4; BCL2L4bcl2-L-4; Bcl-2-like protein 4

Product Datasheets

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COA
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Citations for Mouse Bax MAb (Clone YTH-5B7)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Authors: Muer A, Overkamp T, Gillissen B, Richter A, Pretzsch T, Milojkovic A, Dorken B, Daniel P, Hemmati P
    J Biol Chem, 2012-02-21;287(21):17343-52.
  2. Lymphocyte resistance to lysophosphatidylcholine mediated apoptosis in atherosclerosis.
    Authors: Zurgil N, Afrimzon E, Shafran Y, Shovman O, Gilburd B, Brikman H, Shoenfeld Y, Deutsch M
    Atherosclerosis, 2006-03-27;190(1):73-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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