Mouse Bcl-2 Minus C-Terminus Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB810T Datasheet / COA / SDS

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FAB810T-100UG

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Mouse Bcl-2 Minus C-Terminus Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Bcl‑2 Minus C-Terminus in Western blots.

Source

Monoclonal Rat IgG2b Clone # 121529

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant mouse Bcl-2

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Bcl-2

The Bcl-2 family of proteins plays a crucial role in the regulation of cell death in many eukaryotic systems. Bcl-2 is a 26 kD protein associated with cell survival. Over-expression of Bcl-2 has been shown to promote cell survival by suppressing apoptosis in a number of cells. The ratio of Bcl-2 to other Bcl-2 family members and subcellular localization are believed to modulate the apoptotic process.

Long Name

B Cell Lymphoma/Leukemia 2

Entrez Gene IDs

596 (Human); 12043 (Mouse); 24224 (Rat)

Alternate Names

apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; Bcl2; Bcl-2