Mouse CCL17/TARC Biotinylated Fluorokine Flow Cytometry Kit
Mouse CCL17/TARC Biotinylated Fluorokine Flow Cytometry Kit Summary
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Background: CCL17/TARC
CCL17/TARC is a chemokine that interacts with CCR4 and CCR8 to induce the chemoattraction of activated Th2 cells, basophils, and NK cells. It is produced by thymic dendritic cells, lymph node dendritic cells, monocytes, CD4+ T cells, keratinocytes, fibroblasts, bronchial epithelial cells, and Reed-Sternberg cells. CCL17 promotes Th2 cell recruitment to sites of inflammation and induces platelet aggregation and degranulation.
Citations for Mouse CCL17/TARC Biotinylated Fluorokine Flow Cytometry Kit
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Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs.
Authors: Semmling V, Lukacs-Kornek V, Thaiss CA, Quast T, Hochheiser K, Panzer U, Rossjohn J, Perlmutter P, Cao J, Godfrey DI, Savage PB, Knolle PA, Kolanus W, Forster I, Kurts C
Nat. Immunol., 2010-02-28;11(4):313-20. 2010-02-28
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A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008-04-10;172(5):1209-21. 2008-04-10
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