Mouse CCL21/6Ckine Quantikine ELISA Kit Summary
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Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma
|Intra-Assay Precision||Inter-Assay Precision|
The recovery of mouse 6Ckine spiked to levels throughout the range of the assay was evaluated.
|Sample Type||Average % Recovery||Range %|
|Cell Culture Media (n=4)||96||88-104|
Mouse CCL21/6Ckine ELISA Standard Curve
Preparation and Storage
CCL21, also known as 6Ckine, TCA-4, SLC, Exodus-2, and A21, is a homeostatic chemokine that signals through CCR7 or CXCR3. CCL21 is constitutively presented on initial lymphatic vessels, high endothelial venules (HEV), and lymph node dendritic cells (DC) where it promotes the docking of DC to lymphatic vessels and the retention of T cells by lymph node DC, resulting in T cell priming for activation. Its upregulation during chronic inflammation or tissue damage promotes fibrosis, inflammatory cytokine production, and neuropathic pain. The soluble chemokine is elevated in rheumatoid arthritis synovial fluid and in the serum of coronary artery disease patients.
Citation for Mouse CCL21/6Ckine Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Drainage of senescent astrocytes from brain via meningeal lymphatic routes
Authors: Q Li, Y Chen, W Feng, J Cai, J Gao, F Ge, T Zhou, Z Wang, F Ding, C Marshall, C Sheng, Y Zhang, M Sun, J Shi, M Xiao
Brain, Behavior, and Immunity, 2022;103(0):85-96.
Sample Types: Tissue Homogenates
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