Mouse CCL8/MCP-2 Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAF790

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Product Details
Citations (2)
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Mouse CCL8/MCP-2 Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse CCL8/MCP‑2 in Western blots. In Western blots, less than 1% cross‑reactivity with Brucella melitensis BcsP31 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse CCL8/MCP-2
Glu20-Pro97
Accession # Q9Z121
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse CCL8/MCP‑2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CCL8/MCP-2

CCL8, also known as Monocyte Chemoattractant Protein 2 (MCP-2), is an inflammatory CC chemokine that attracts monocytes, eosinophils and basophils. It is produced by many cell types and signals through interactions with CCR1, CCR2, CCR3 and CCR5.

Entrez Gene IDs
6355 (Human); 20307 (Mouse)
Alternate Names
C-C motif chemokine 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; member 8 (monocyte chemotactic protein 2); monocyte chemoattractant protein 2; SCYA10; small-inducible cytokine A8

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Citations for Mouse CCL8/MCP-2 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Pathogenic roles and therapeutic potential of the CCL8-CCR8 axis in a murine model of IgG4-related sialadenitis
    Authors: F Honda, H Tsuboi, Y Ono, S Abe, H Takahashi, K Ito, K Yamada, M Kawano, Y Kondo, K Asano, M Tanaka, M Malissen, B Malissen, I Matsumoto, T Sumida
    Arthritis Research & Therapy, 2021-08-14;23(1):214.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  2. The chemokine receptor CCR8 promotes the migration of dendritic cells into the lymph node parenchyma to initiate the allergic immune response.
    Authors: Caroline L. Sokol, Ryan B. Camire, Michael C. Jones, Andrew D. Luster
    Immunity

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