Mouse CCR7 PE-conjugated Antibody
Mouse CCR7 PE-conjugated Antibody Summary
Accession # NP_031745
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of CCR7 in Mouse Splenoctyes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody (Catalog # FAB4841A) and either (A) Rat Anti-Mouse CCR7 PE-conjugated Monoclonal Antibody (Catalog # FAB3477P) or (B) Rat IgG2APhycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CCR7
CCR7 (Chemokine Receptor 7; also CD197) is a 7 transmembrane (7TM) G protein-coupled chemokine receptor for the homeostatic chemokines CCL19/MIP-3 beta and CCL21/6Ckine. CCL19 and CCL21 are constitutively expressed by high endothelial venule epithelial cells or fibroblastic reticular cells in secondary lymphoid organs. CCR7 is upregulated on dendritic cells, naïve and memory T cells, Treg, NK cells, and B cells following inflammatory stimulation. Its expression enables the function of immune cell trafficking to and retention in regional lymph nodes for expansion of the adaptive immune response. Mouse CCR7 shares 87% amino acid sequence identity with human CCR7.
Product Datasheets
Citations for Mouse CCR7 PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 5
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Contribution of Heparan Sulphate Binding in CCL21-Mediated Migration of Breast Cancer Cells
Authors: I Del Molino, A Meeson, K Cooke, MI Malki, B Barron-Mil, JA Kirby, S Ali
Cancers, 2021;13(14):.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Zearalenone inhibits T cell chemotaxis by inhibiting cell adhesion and migration related proteins
Authors: G Cai, S Pan, N Feng, H Zou, J Gu, Y Yuan, X Liu, Z Liu, J Bian
Ecotoxicol. Environ. Saf., 2019;175(0):263-271.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mature dendritic cell derived from cryopreserved immature dendritic cell shows impaired homing ability and reduced anti-viral therapeutic effects
Sci Rep, 2016;6(0):39071.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Immune suppressive effects of tonsil-derived mesenchymal stem cells on mouse bone-marrow-derived dendritic cells.
Authors: Park, Minhwa, Kim, Yu-Hee, Ryu, Jung-Hwa, Woo, So-Youn, Ryu, Kyung-Ha
Stem Cells Int, 2015;2015(0):106540.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFkappaB and ERK.
Authors: Badr G, Sayed A, Abdel-Maksoud M, Mohamed A, El-Amir A, Abdel-Ghaffar F, Al-Quraishy S, Mahmoud M
PLoS ONE, 2015;10(4):e0125340.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry
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