Mouse DCAR/CLEC4B Antibody

Catalog # Availability Size / Price Qty
Product Details
Citations (2)
Supplemental Products

Mouse DCAR/CLEC4B Antibody Summary

Species Reactivity
Detects mouse DCAR/CLEC4B in direct ELISAs.
Monoclonal Rat IgG2A Clone # 349214
Protein A or G purified from hybridoma culture supernatant
Mouse myeloma cell line NS0-derived recombinant mouse DCAR/CLEC4B
Accession # AAR13070
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Flow Cytometry
0.25 µg/106 cells
Mouse bone marrow‑derived dendritic cells
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: DCAR/CLEC4B

Dendritic Cell immuno-Activating Receptor alpha isoform (DCAR) is a type II membrane protein belonging to the C-type lectin domain family and is designated CLEC4B. Two isoforms of DCAR exist, a 209 amino acid (aa) residue alpha isoform and a 176 aa form with a 33 aa deletion at the membrane proximal region of the extracellular domain. The DCAR extracellular domain contains a carbohydrate-recognition domain (CRD) that shares 91% amino acid sequence identity with the CRD of DCIR/CLEC4A. The DCAR intracellular domain is very short and lacks the ITIM motif found in DCIR. DCAR and DCIR are considered paired immunoregulatory receptors where DCAR activates through the ITAM of its associated adaptor molecule FcR gamma.

Long Name
Dendritic Cell Immunoreceptor
Entrez Gene IDs
69810 (Mouse)
Alternate Names

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Citations for Mouse DCAR/CLEC4B Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Structural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR
    Authors: Z Omahdi, Y Horikawa, M Nagae, K Toyonaga, A Imamura, K Takato, T Teramoto, H Ishida, Y Kakuta, S Yamasaki
    J. Biol. Chem., 2020-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells.
    Authors: Barrett NA, Maekawa A, Rahman OM, Austen KF, Kanaoka Y
    J. Immunol., 2009-01-15;182(2):1119-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry


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