ErbB3, also called Her3 (human epidermal growth factor receptor 3) in humans, is a type I transmembrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB3 binds neuregulins NRG1 and NRG2, but lacks a working kinase domain; heterodimerization with another ErbB receptor is required for signaling. ErbB3 is important in development of Schwann cells, neural crest cells, heart valves and the sympathetic nervous system. When expressed with ErbB2 in breast, skin, ovary and gastrointestinal tumors, ErbB3 is a potent mitogen.
Mouse ErbB3/Her3 (NP_034283) VersaClone cDNA
R&D Systems | Catalog # RDC1061
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: ErbB3/Her3
Long Name
Receptor Tyrosine Protein Kinase ErbB3
Alternate Names
HER3
Gene Symbol
ERBB3
UniProt
Additional ErbB3/Her3 Products
Product Documents for Mouse ErbB3/Her3 (NP_034283) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Mouse ErbB3/Her3 (NP_034283) VersaClone cDNA
For research use only
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