Mouse ICAM-2/CD102 Alexa Fluor® 594-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: ICAM-2/CD102

Intercellular Adhesion Molecule-2 (ICAM-2, also known as CD102), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration. The mouse and human ICAM-2 proteins share 60% amino acid identity. Human LFA-1 binds equally well to human or mouse ICAM-2.

Product Datasheets

Related Research Areas

• Acute Lymphoblastic Leukemia
• Adhesion Molecules
• Adhesion Molecules in Angiogenesis
• Adhesion Molecules on Endothelial Cells
• Adhesive Interactions in Allergy and Asthma
• B Cell Chemotaxis, Migration, and Adhesion
• Dendritic Cell Pathogen Recognition/Uptake
• Endothelial Cell Markers
• Immunoglobulin Superfamily CAMs
• Platelet Adhesion Molecules
• T Cell Migration/Adhesion