Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

Flow Cytometry

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all IFITM3/Fragilis Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse IFITM3/Fragilis
Asn2-His57
Accession # NP_079654

Specificity

Detects mouse IFITM3/Fragilis in Western blots. In Western blots, approximately 50% cross-reactivity with recombinant human IFITM3 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse IFITM3/Fragilis Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse IFITM3/Fragilis

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IFITM3/Fragilis

Mouse IFITM3 (also Fragilis) is a 137 amino acids (aa) 2-transmembrane protein that belongs to the Fragilis family of interferon-inducible genes. It contains two terminal extracellular domains (aa's 1-57 and 131-137) and one cytoplasmic region that potentially allows for multiple phosphorylations. The N-terminal extracellular region of mouse IFITM3 is 54%, 91% and 58% aa identical to the equivalent region in bovine, rat and human IFITM3, respectively. IFITM3 seems to be involved in primordial germ cell clustering and regionalization.

Long Name

Interferon-induced Transmembrane Protein 3

Alternate Names

Fragilis, IP15, mil-1

Entrez Gene IDs

10410 (Human); 66141 (Mouse)

Gene Symbol

IFITM3

UniProt

NP_079654

Additional IFITM3/Fragilis Products

Product Documents for Mouse IFITM3/Fragilis Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse IFITM3/Fragilis Biotinylated Antibody

For research use only

Related Research Areas

Primordial and Mature Germ Cells

Citations for Mouse IFITM3/Fragilis Biotinylated Antibody

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