Mouse IFN-beta Fluorescein MAb (Clone RMMB-1)

Name: Mouse IFN-beta Fluorescein MAb (Clone RMMB-1)
Brand: R&D Systems
SKU: 22400-3

Catalog #: 22400-3 Datasheet / COA / SDS

Discontinued Product

22400-3 has been discontinued.

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IFN-beta Fluorescein MAb (Clone RMMB-1) Summary

Species Reactivity

Mouse

Source

Monoclonal Rat IgG2a Clone # RMMB-1

Formulation

phosphate-buffered saline (PBS) containing 1% BSA and 0.05% Kathon as a preservative, pH 7.2

Label

Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

Please refer to the PDF datasheet for specifications.

Immunohistochemistry

Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-beta

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Long Name

Interferon beta

Entrez Gene IDs

3456 (Human); 15977 (Mouse); 24481 (Rat)

Alternate Names

Fibroblast interferon; IFB; IFBIFNB; IFF; IFNB; IFNB1; IFNbeta; IFN-beta; interferon beta; interferon, beta 1, fibroblast; MGC96956