Mouse NGFR/TNFRSF16 (Q9Z0W1) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Mouse NGFR/TNFRSF16 (Q9Z0W1) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: NGFR/TNFRSF16

The low affinity nerve growth factor receptor (NGF R), is a type I transmembrane protein that belongs to the tumor necrosis factor receptor family1 and has been designated TNFRSF16. The NGF receptor is also known as p75 NTR (neurotrophin receptor) because of its ability to bind at low affinity not only to NGF, but also other neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5. NGF R also binds several myelin derived proteins (Nogo, myelin associated glycoprotein, and myelin oligodendrocyte glycoprotein) as a co-receptor with Nogo receptor.

The NGF receptor is a 75 kDa protein that is expressed in neuronal axons, Schwanns cells and perineural cells of peripheral nerves. Neural crest stem cells have been isolated based on their surface expression of NGF R. In addition, neuroepithelial-derived NGF receptor positive cells have also been demonstrated to be able to differentiate into neurons, smooth muscle and Schwann cells in culture. The expression of the NGF receptor has also been used as a marker to identify mesenchymal precursors as well as hepatic stellate cells.

Long Name
Nerve Growth Factor Receptor
Entrez Gene IDs
4804 (Human); 18053 (Mouse); 117089 (Rat)
Alternate Names
CD271 antigen; CD271; Gp80-LNGFR; member 16; nerve growth factor receptor; NGF R; NGF receptor; NGFR; p75 ICD; p75 NTR; TNFRSF16; TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16); tumor necrosis factor receptor superfamily member 16


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Tocris Small Molecules

PD 90780

Ro 08-2750

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