Mouse OCIL/CLEC2d Biotinylated Antibody
Mouse OCIL/CLEC2d Biotinylated Antibody Summary
Accession # Q91V08
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Mouse OCIL, also known as C-type lectin-related b (Clrb), is a type II transmembrane protein belonging to the natural killer (NK) cell receptor group of the C-type lectin superfamily. It is found on hematopoietic cells, osteoclasts and chondrocytes. OCIL preferentially binds high molecular weight, sulfated glycosaminoglycans and is a ligand for the mouse NK R-PIB/D receptor. OCIL blocks osteoclast differentiation. Engagement of OCIL with NK R-PIB/D on NK cells inhibits NK cell functions. The extracellular domain of mouse OCIL shares 49% and 71% amino acid sequence identity with rat and human OCIL, respectively.
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