Mouse OCIL/CLEC2d Antibody

Catalog # Availability Size / Price Qty
AF3376
AF3376-SP

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Product Details
Citations (1)
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Mouse OCIL/CLEC2d Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse OCIL/CLEC2d in direct ELISAs and Western blots. In Western blots, approximately 35% cross-reactivity with recombinant mouse OCILRP2 is observed and less than 2% cross-reactivity with recombinant human OCIL is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse OCIL/CLEC2d
Ala65-Ser207
Accession # Q91V08
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse OCIL/CLEC2d

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OCIL/CLEC2d

Mouse OCIL, also known as C-type lectin-related b (Clrb), is a type II transmembrane protein belonging to the natural killer (NK) cell receptor group of the C-type lectin superfamily. It is found on hematopoietic cells, osteoclasts and chondrocytes. OCIL preferentially binds high molecular weight, sulfated glycosaminoglycans and is a ligand for the mouse NK R-PIB/D receptor. OCIL blocks osteoclast differentiation. Engagement of OCIL with NK R-PIB/D on NK cells inhibits NK cell functions. The extracellular domain of mouse OCIL shares 49% and 71% amino acid sequence identity with rat and human OCIL, respectively.

Long Name
Osteoclast Inhibitory Lectin
Entrez Gene IDs
29121 (Human); 93694 (Mouse)
Alternate Names
CLAXLLT-1; CLEC2D; C-type lectin domain family 2 member D; C-type lectin domain family 2, member D; C-type lectin related f; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT1; LLT1Osteoclast inhibitory lectin; OCIL; OCILmember D

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Citation for Mouse OCIL/CLEC2d Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

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