Mouse OCILRP2/CLEC2i Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAF3370

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Mouse OCILRP2/CLEC2i Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse OCILRP2/CLEC2i in Western blots. In Western blots, approximately 25% cross‑reactivity with recombinant mouse OCIL is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse OCILRP2/CLEC2i
Thr77-Val217
Accession # Q9WVF9
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse OCILRP2/CLEC2i

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: OCILRP2/CLEC2i

OCILRP2, also known as CLRG (C-type lectin related g) and CLEC2i (C-type lectin domain family 2, member i), is a type II transmembrane protein whose gene has been mapped to the natural killer gene complex (NKC) on mouse chromosome 6. By alternative splicing, multiple isoforms exist. OCIL RP2 is expressed on osteoclasts, chondrocytes and lymphoid cell types. It is a ligand for NKrp1f (KLRB1f), another NK receptor on the NKC. OCILRP2 inhibits osteoclast formation and can affect NK cell functions. The extracellular domain of mouse OCILRP2 shares 79% and 74% amino acid sequence identity with that of mouse OCILRP1 and OCIL, respectively. A human OCILRP2 ortholog has not been identified.

Long Name
Osteoclast Inhibitory Lectin Related Protein 2
Entrez Gene IDs
93675 (Mouse)
Alternate Names
CLAX; CLEC2i; CLRG; LLT1; OCIL; OCILRP2

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