Mouse Plasminogen Kringle 5 Antibody

Catalog # Availability Size / Price Qty
MAB742
MAB742-SP
Product Details
Citations (1)
FAQs
Supplemental Products
Reviews

Mouse Plasminogen Kringle 5 Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse Plasminogen Kringle 5 in direct ELISAs and Western blots. In direct ELISAs, no cross‑reactivity with recombinant human Plasminogen Kringle 5 is observed.
Source
Monoclonal Rat IgG1 Clone # 120304
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant mouse Plasminogen Kringle 5
Cys481-Ala563
Accession # AAA50168
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Mouse Plasminogen Kringle 5

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Plasminogen Kringle 5

Plasminogen is a coenzyme that has five triple disulfide-linked kringle domains. It is converted to plasmin by plasminogen activators. Internal fragments of plasminogen, including the naturally occurring angiostatin isoforms and Kringle 5, can also be generated by proteolytic cleavage. These internal fragments have been shown to be potent angiogenesis inhibitors (1).

References
  1. Cao, Y. et al. (1997) J. Biol. Chem. 272:22924.
Entrez Gene IDs
5340 (Human); 18815 (Mouse); 85253 (Rat)
Alternate Names
Plasminogen Kringle 5

Product Datasheets

Citation for Mouse Plasminogen Kringle 5 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Histone H2B as a functionally important plasminogen receptor on macrophages.
    Authors: Das R, Burke T, Plow EF
    Blood, 2007;110(10):3763-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC

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