Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all Plasminogen Kringle 5 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant mouse Plasminogen Kringle 5
Cys481-Ala563
Accession # AAA50168

Specificity

Detects mouse Plasminogen Kringle 5 in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human Angiostatin (Kringle 1‑3) is observed. This antibody is expected to show cross-reactivity with mouse Plasminogen.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse Plasminogen Kringle 5 Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse Plasminogen Kringle 5

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Plasminogen Kringle 5

Plasminogen is a coenzyme that has five triple disulfide-linked kringle domains. It is converted to plasmin by plasminogen activators. Internal fragments of plasminogen, including the naturally occurring angiostatin isoforms and Kringle 5, can also be generated by proteolytic cleavage. These internal fragments have been shown to be potent angiogenesis inhibitors (1).

References

  1. Cao, Y. et al. (1997) J. Biol. Chem. 272:22924.

Alternate Names

HAE4

Entrez Gene IDs

5340 (Human); 18815 (Mouse); 85253 (Rat)

Gene Symbol

PLG

UniProt

AAA50168

Additional Plasminogen Kringle 5 Products

Product Documents for Mouse Plasminogen Kringle 5 Biotinylated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse Plasminogen Kringle 5 Biotinylated Antibody

For research use only

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FAQs

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Associated Pathways

Blood Coagulation Signaling Pathways Blood Coagulation Signaling Pathway Thumbnail