Mouse Plasminogen Kringle 5 Antibody

Catalog # Availability Size / Price Qty
Product Details
Citations (1)
Supplemental Products

Mouse Plasminogen Kringle 5 Antibody Summary

Species Reactivity
Detects mouse Plasminogen Kringle 5 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human Angiostatin (Kringle 1‑3) is observed. This antibody is expected to show cross-reactivity with mouse plasminogen.
Polyclonal Goat IgG
Antigen Affinity-purified
E. coli-derived recombinant mouse Plasminogen Kringle 5
Accession # AAA50168
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.01 EU per 1 μg of the antibody by the LAL method.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Mouse Plasminogen Kringle 5
5-15 µg/mL
Immersion fixed frozen sections of mouse embryo (E15)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Plasminogen Kringle 5

Plasminogen is a coenzyme that has five triple disulfide-linked kringle domains. It is converted to plasmin by plasminogen activators. Internal fragments of plasminogen, including the naturally occurring angiostatin isoforms and Kringle 5, can also be generated by proteolytic cleavage. These internal fragments have been shown to be potent angiogenesis inhibitors (1).

  1. Cao, Y. et al. (1997) J. Biol. Chem. 272:22924.
Entrez Gene IDs
5340 (Human); 18815 (Mouse); 85253 (Rat)
Alternate Names
HAE4; Plasminogen Kringle 5

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Citation for Mouse Plasminogen Kringle 5 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode.
    Authors: Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I, Stravalaci M, Pasqualini F, Laface I, Valentino S, Tartari S, Ponzetta A, Maina V, Barbieri S, Tremoli E, Catapano A, Norata G, Bottazzi B, Garlanda C, Mantovani A
    J Exp Med, 2015-05-11;212(6):905-25.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot


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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

Goat IgG (H+L) Antibody


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