Mouse/Rat APE Primer Pair

Catalog #: RDP-171 Datasheet / COA / SDS

Discontinued Product

RDP-171 has been discontinued.
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Mouse/Rat APE Primer Pair Summary

Specifications

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Mouse Rat

Product Datasheets

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Background: APE

Apurinic/Apyrimidinic Endonuclease (APE), also known as redox factor 1 (Ref-1), is a multifunctional enzyme involved in both DNA repair and transcription factor binding. The C-terminal region is responsible for base excision repair activities. This repair activity, however, is suppressed by phosphorylation. The N-terminal region of APE may regulate the DNA binding capabilities of a variety of transcription factors through redox stimulation.

Long Name
Apurinic/Apyrimidinic Endonuclease
Entrez Gene IDs
328 (Human); 305605 (Rat)
Alternate Names
AP endonuclease 1; APE; APE1; APE-1; APEAPEX nuclease (multifunctional DNA repair enzyme); APENAP endonuclease class I; APEX deoxyribonuclease (apurinic or apyrimidinic); APEX nuclease (multifunctional DNA repair enzyme) 1; APEX nuclease; APEX1; Apurinic-apyrimidinic endonuclease 1; APXAP lyase; DNA-(apurinic or apyrimidinic site) lyase; EC 3.1; EC 4.2.99.18; HAP1apurinic/apyrimidinic (abasic) endonuclease; multifunctional DNA repair enzyme; protein REF-1; redox factor 1; Redox factor-1; REF1 apurinic/apyrimidinic exonuclease; REF-1

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