Mouse SEZ6/BSRP-C Biotinylated Antibody

Catalog # Availability Size / Price Qty
BAF4989
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Mouse SEZ6/BSRP-C Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse SEZ6/BSRP-C in Western blots. In Western blots, less than 2% cross-reactivity with recombinant mouse (rm) BSRP-A and rmBSRP-B is observed.
Source
Polyclonal Sheep IgG
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse SEZ6/BSRP-C

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: SEZ6/BSRP-C

BSRP-C (Brain-specific receptor-like protein C; also SEZ6) is a 150 kDa member of the BSRP family of proteins. It is expressed on neurons and exerts an antibranching effect relative to neurite extension. Mature mouse BSRP-C is a 974 amino acid (aa) type I transmembrane glycoprotein. It contains an extracellular domain (ECD) of at least 876 amino acids (aa 18‑893). The ECD shows three CUB domains and five short consensus repeats (SCRs). There are two splice variants for BSRP-C. One is soluble, and shows an 18 aa substitution for aa 588‑991, while a second shows a deletion of aa 895‑907 plus a 9 aa substitution for aa 982‑991. Over aa 19‑902, mouse BSRP-C is 91% aa identical to human BSRP-C.

Long Name
Seizure Related 6/Brain-specific Receptor-like Protein-C
Entrez Gene IDs
124925 (Human); 20370 (Mouse); 192247 (Rat)
Alternate Names
BSRPC; BSRP-C; hSEZ-6; seizure related 6 homolog (mouse); SEZ6

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