Mouse TGF-beta RII Alexa Fluor® 488-conjugated Antibody

Catalog #: FAB532G Datasheet / COA / SDS

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FAB532G-100UG

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All TGF-beta RII Antibodies

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Mouse TGF-beta RII Alexa Fluor® 488-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse TGF-beta RII in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with with recombinant rat MIS RII, recombinant mouse TGF-beta RI, recombinant human (rh) TGF-beta RII, rhTGF-beta RIIb, or rhTGF-beta RIII.

Source

Monoclonal Rat IgG2b Clone # 129502

Purification

Protein A or G purified

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse TGF-Î² RII
Ile24-Asp184
Accession # Q62312

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 488 (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TGF-beta RII

TGF-beta RII is a membrane-bound serine/threonine kinase. It associates with TGF-beta RI to generate a heterodimeric signaling complex that transduces TGF-beta signals. This receptor binds TGF-beta 1 and TGF-beta 3 with high affinity and TGF-beta 2 with much lower affinity and is expressed by most cell types.

Long Name

Transforming Growth Factor beta Receptor II

Entrez Gene IDs

7048 (Human); 21813 (Mouse)

Alternate Names

AAT3; EC 2.7.11; EC 2.7.11.30; FAA3; HNPCC6; LDS1B; LDS2B; MFS2; RIIC; TAAD2; tbetaR-II; TGF-beta receptor type II; TGF-beta receptor type IIB; TGF-beta receptor type-2; TGF-beta RII; TGF-beta type II receptor; TGFbetaRII; TGFbeta-RII; TGFBR2; TGF-bRII; TGFR-2; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; transforming growth factor, beta receptor II (70/80kDa); transforming growth factor, beta receptor II (70-80kD); Transforming growth factor-beta receptor type II