Mouse XCL1/Lymphotactin Antibody
Mouse XCL1/Lymphotactin Antibody Summary
Accession # AAA56752
Mouse XCL1/Lymphotactin Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Mouse XCL1, also known as Lymphotactin, and its human homologue (also named human SCM-1 and ATAC) belong to the C or gamma subfamily of chemokines. The C chemokines lack two (the 1st and 3rd) of the four invariant cysteine residues normally found in the CC and CXC chemokines and have an extended carboxy terminus. Mouse XCL1 encodes a 114 amino acid residue precursor protein with a 21 amino acid residue predicted signal peptide. The expression of XCL1 is restricted to activated mouse pro-T cells and to activated, class I MHC restricted T cells. The gene for XCL1 has been mapped to chromosome 1 in both human and mouse. Recombinant mouse XCL1 has been shown to have chemotactic activity for lymphocytes, NK cells and mouse splenocytes.
- Kelner, G. et al. (1994) Science 266:1395.
- Hedrick, J.A. et al. (1997) J. Immunol. 158:1533.
Citations for Mouse XCL1/Lymphotactin Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Authors: A Deczkowska, E David, P Ramadori, D Pfister, M Safran, B At The, A Giladi, DA Jaitin, O Barboy, M Cohen, I Yofe, C Gur, S Shlomi-Lou, S Henri, Y Suhail, M Qiu, S Kam, H Hermon, E Lahat, G Ben Yakov, O Cohen-Ezra, Y Davidov, M Likhter, D Goitein, S Roth, A Weber, B Malissen, A Weiner, Z Ben-Ari, M Heikenwäld, E Elinav, I Amit
Nature Medicine, 2021;0(0):.
Sample Types: In Vivo
NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
Authors: JP Böttcher, E Bonavita, P Chakravart, H Blees, M Cabeza-Cab, S Sammicheli, NC Rogers, E Sahai, S Zelenay, C Reis E Sou
Sample Types: In Vivo
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