imidazoline receptor and α2
-adrenergic agonist; displays 40-fold higher affinity for I1
receptors versus α2
-adrenoceptors. Centrally acting antihypertensive agent.
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All Tocris products are intended for laboratory research use only.
Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and α2-adrenoceptors.
Schafer et al.
Imidazoline receptors but not a2-adrenoceptors are regulated in spontaneously hypertensive rat heart by chronic moxonidine treatment.
El-Ayoubi et al.
Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine.
Chan et al.