Chemical Name:N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine hydrochloride
Biological Activity Potent inhibitor of microtubule formation (IC50 = 1.5 - 3.4 nM); inhibits polymerization of tubulin in vitro and disrupts microtubule formation in several cancer cell lines. Inhibits tumor growth in vitro and in vivo; exhibits pro-apoptotic characteristics. Brain penetrant.
Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT
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