MRS 2179 tetrasodium salt

Tocris Bioscience | Catalog # 0900

Selective P2Y1 antagonist
Tocris Bioscience

Key Product Details

Description

Selective P2Y1 antagonist
View all P2Y Receptor Antagonists »

Product Description

MRS 2179 tetrasodium salt is a competitive antagonist at P2Y1 receptors (KB = 100 nM). Selective over P2X1 (IC50 = 1.15 μM), P2X3 (IC50 = 12.9 μM), P2X2, P2X4, P2Y2, P2Y4 and P2Y6 receptors. Inhibits the upregulation of NTPDase1 by ATPγS.

Product Specifications for MRS 2179 tetrasodium salt

Molecular Weight

513.16

Formula

C11H13N5O9P2Na4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2'-Deoxy-N6-methyladenosine 3',5'-bisphosphate tetrasodium salt

CAS Number

1454889-37-2

PubChem ID

90479745

InChI Key

XLPQPYQWGFCKEY-IDAKGYGSSA-J

SMILES

[Na+].[Na+].[Na+].[Na+].CNC1=NC=NC2=C1N=CN2[C@@H]1C[C@H](OP([O-])([O-])=O)[C@@H](COP([O-])([O-])=O)O1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 25.66 50

Preparing Stock Solutions for MRS 2179 tetrasodium salt

The following data is based on the product molecular weight 513.16.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 3.90 mL 19.49 mL 38.97 mL
2.5 mM 0.78 mL 3.90 mL 7.79 mL
5 mM 0.39 mL 1.95 mL 3.90 mL
25 mM 0.08 mL 0.39 mL 0.78 mL

Calculators

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Product Documents for MRS 2179 tetrasodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for MRS 2179 tetrasodium salt

For research use only

Related Research Areas

Bioactive Lipids and Receptors

Citations for MRS 2179 tetrasodium salt

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  • works well
    Name: Karthik krishnamurthy
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: astrocytes
    Verified Customer | Posted 11/08/2018
    25 micromolar of MRS2179 was bath applied.
    used to block P2Y1 receptor mediated calcium entry in mouse astrocytes stimulated with 2MeSADP
    MRS 2179 tetrasodium salt 0900

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