Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

Novus Biologicals | Catalog # NB100-41399

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Cited:

Rat

Predicted:

Canine (100%), Human (100%). Backed by our 100% Guarantee.

Applications

Validated:

Western Blot, Peptide ELISA

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all CHRM1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-DKRRWRKIPKRPGSVH corresponding to C-Terminus according to NP_000729.2.

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 21389686).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399]

Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399]

Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399] - Staining of mouse heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx 50 kDa band observed in mouse heart lysates (calculated MW of 51.4 kDa according to NP_000729.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CHRM1

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Long Name

Cholinergic Receptor Muscarinic 1

Alternate Names

HM1, M1, M1R, mAChR M1

Entrez Gene IDs

1128 (Human); 12669 (Mouse); 25229 (Rat)

Gene Symbol

CHRM1

UniProt

NP_000729.2 (Human)

Additional CHRM1 Products

Product Documents for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

Certificate of Analysis

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Product Specific Notices for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody

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