22 results for "CHRM1" in Products
CHRM1 Products
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP1-87466]](https://resources.rndsystems.com/images/products/Muscarinic-Acetylcholine-Receptor-M1-CHRM1-Antibody-Immunohistochemistry-Paraffin-NBP1-87466-img0009.jpg "Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP1-87466]")
Highly selective M1 antagonist
| Chemical Name: | N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #HL3933 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 AntibodyAzide and BSA Free [NBP2-94811]](https://resources.rndsystems.com/images/products/Muscarinic-Acetylcholine-Receptor-M1-CHRM1-Antibody-Western-Blot-NBP2-94811-img0006.jpg "Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 AntibodyAzide and BSA Free [NBP2-94811]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 AntibodyAzide and BSA Free [NBP2-94511]](https://resources.rndsystems.com/images/products/Muscarinic-Acetylcholine-Receptor-M1-CHRM1-Antibody-Western-Blot-NBP2-94511-img0001.jpg "Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 AntibodyAzide and BSA Free [NBP2-94511]")
Non-selective cholinergic agonist
| Alternate Names: | Carbachol |
| Chemical Name: | (2-Hydroxyethyl)trimethylammonium chloride carbamate |
Muscarinic agonist
| Chemical Name: | (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride |
| Purity: | ≥98% |
Potent, selective M1 antagonist
| Chemical Name: | 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride |
| Purity: | ≥98% |
Muscarinic agonist
| Chemical Name: | 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate |
| Purity: | ≥98% |
Functionally biased muscarinic M4 receptor agonist
| Chemical Name: | 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine oxalate |
| Purity: | ≥98% |
| Reactivity: | Human |
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399]](https://resources.rndsystems.com/images/products/Muscarinic-Acetylcholine-Receptor-M1-CHRM1-Antibody-Western-Blot-NB100-41399-img0001.jpg "Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NB100-41399]")
Selective M1 muscarinic agonist
| Chemical Name: | 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium chloride |
| Purity: | ≥99% |
Selective M1 agonist
| Alternate Names: | AF 102B,SNI 2011 |
| Chemical Name: | cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride |
Positive allosteric modulator of M1 receptors
| Chemical Name: | 4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester hydrochloride |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 AntibodyAzide and BSA Free [NBP2-93968]](https://resources.rndsystems.com/images/products/Muscarinic-Acetylcholine-Receptor-M1-CHRM1-Antibody-Western-Blot-NBP2-93968-img0002.jpg "Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 AntibodyAzide and BSA Free [NBP2-93968]")
| Reactivity: | Mouse |
| Sensitivity: | 0.47 ng/mL |
| Assay Range: | 0.78 - 50 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 0.19 ng/mL |
| Assay Range: | 0.31 - 20 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Overexpression Lysate [NBL1-09173]](https://resources.rndsystems.com/images/products/Muscarinic-Acetylcholine-Receptor-1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-09173-img0002.jpg "Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Overexpression Lysate [NBL1-09173]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP2-85340]](https://resources.rndsystems.com/images/products/Muscarinic-Acetylcholine-Receptor-M1-CHRM1-Antibody-Western-Blot-NBP2-85340-img0001.jpg "Western Blot: Muscarinic Acetylcholine Receptor M1/CHRM1 Antibody [NBP2-85340]")
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | AP |
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |