MuSK Antibody (10A4)

Novus Biologicals | Catalog # NBP1-47441

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 10A4
View all MuSK Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant extracellular fragment of human MuSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

97 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for MuSK Antibody (10A4)

Immunocytochemistry/ Immunofluorescence: MuSK Antibody (10A4) - BSA Free [NBP1-47441]

Immunocytochemistry/ Immunofluorescence: MuSK Antibody (10A4) - BSA Free [NBP1-47441]

Immunocytochemistry/Immunofluorescence: MuSK Antibody (10A4) [NBP1-47441] - Human neurons stained with MuSK antibody. ICC/IFF image submitted by a verified customer review.
Immunohistochemistry-Paraffin: MuSK Antibody (10A4) - BSA Free [NBP1-47441]

Immunohistochemistry-Paraffin: MuSK Antibody (10A4) - BSA Free [NBP1-47441]

Immunohistochemistry-Paraffin: MuSK Antibody (10A4) [NBP1-47441] - Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using anti-MUSK antibody with DAB staining.
Immunocytochemistry/ Immunofluorescence: MuSK Antibody (10A4) - BSA Free [NBP1-47441]

Immunocytochemistry/ Immunofluorescence: MuSK Antibody (10A4) - BSA Free [NBP1-47441]

Immunocytochemistry/Immunofluorescence: MuSK Antibody (10A4) [NBP1-47441] - Confocal immunofluorescence analysis of HEK293 cells transfected with extracellular MUSK (aa24-209)-hIgGFc using anti-MUSK monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye.

Applications for MuSK Antibody (10A4)

Application
Recommended Usage

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:200-1000

Reviewed Applications

Read 1 review rated 5 using NBP1-47441 in the following applications:

Formulation, Preparation, and Storage

Purification

Ascites

Formulation

Ascites

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MuSK

Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM]

Long Name

Muscle-specific Receptor Tyrosine Kinase

Alternate Names

EC 2.7.10, EC 2.7.10.1, MGC126323, MGC126324, muscle, skeletal, receptor tyrosine kinase, MuSK, skeletal receptor tyrosine-protein kinase

Gene Symbol

MUSK

Additional MuSK Products

Product Documents for MuSK Antibody (10A4)

Certificate of Analysis

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Product Specific Notices for MuSK Antibody (10A4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for MuSK Antibody (10A4) (1)

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Customer Images

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  • MuSK Antibody (10A4)
    Name: Anonymous
    Application: Immunofluorescence
    Sample Tested: neurons
    Species: Human
    Verified Customer | Posted 08/12/2021
    Immunofluorescence, neurons
    MuSK Antibody (10A4) NBP1-47441

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Protocols

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FAQs

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