Q: Are there any MVP antibodies that will recognize mouse and can be used for immunofluorescence?

A: At this time we do not have an MVP antibody that will recognize mouse and has been used for immunofluorescence. If you would like to try an antibody in an untested species or application you would qualify for our Innovator's Reward program. Through this program if you complete an online review with image, detailing your positive or negative results we will send you a discount voucher for 100% of the purchase price of the reviewed product.

MVP Antibody (1014)

Novus Biologicals | Catalog # NBP2-44400

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Product Documents

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Product Specifications
Scientific Data
Applications
Flow Cytometry
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 1014

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Product Specifications

Immunogen

proteins precipitated from human breast cancer MCF-7 cells

Localization

Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-11555)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for MVP Antibody (1014)

Western Blot: MVP Antibody (1014) [NBP2-44400]

Western Blot: MVP Antibody (1014) [NBP2-44400] - Western Blot Analysis of human HeLa cell lysate using MVP Antibody (1014).

Immunocytochemistry/ Immunofluorescence: MVP Antibody (1014) [NBP2-44400]

Immunocytochemistry/Immunofluorescence: MVP Antibody (1014) [NBP2-44400] - Immunofluorescence Analysis of A549 cells labeling MVP with MVP Antibody (1014) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Red Dot (Red).

Applications for MVP Antibody (1014)

Application

Recommended Usage

Flow Cytometry

1-2 ug/million cells

Immunocytochemistry/ Immunofluorescence

1-2 ug/ml

Application Notes

Optimal dilution for a specific application should be determined.

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Advanced Features

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Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: MVP

MVP encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

Alternate Names

LRPVAULT1, Lung resistance-related protein, major vault protein

Gene Symbol

MVP

UniProt

Q14764 (Human)

Additional MVP Products

Product Documents for MVP Antibody (1014)

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Certificate of Analysis

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Product Specific Notices for MVP Antibody (1014)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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