Myotilin Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-38361

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Myotilin Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Myotilin Antibody - BSA Free

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human testis.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human skeletal muscle shows high expression.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human skin shows low expression as expected.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining in human skeletal muscle and skin tissues using anti-MYOT antibody. Corresponding MYOT RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human cerebral cortex, lymph node, skeletal muscle and testis using Anti-MYOT antibody NBP2-38361 (A) shows similar protein distribution across tissues to independent antibody NBP1-87851 (B).
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human lymph node.
Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361]

Immunohistochemistry-Paraffin: Myotilin Antibody [NBP2-38361] - Staining of human cerebral cortex.

Applications for Myotilin Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Myotilin

Striated muscle sarcomeres are highly organized structures composed of actin (thin) and myosin (thick) filaments that slide past each other during contraction. The integrity of sarcomeres is controlled by a set of structural proteins, among which are titin (TTN; MIM 188840), a giant molecule that contains several immunoglobulin (Ig)-like domains and associates with thin and thick filaments, and alpha-actinin (ACTN1; MIM 102575), an actin cross-linking protein. Mutations in several sarcomeric and sarcolemmal proteins have been shown to result in muscular dystrophy and cardiomyopathy.[supplied by OMIM]

Alternate Names

57 kDa cytoskeletal protein, LGMD1A, limb-girdle muscular dystrophy 1A (autosomal dominant), Myofibrillar titin-like Ig domains protein, myotilin, Titin immunoglobulin domain protein, titin immunoglobulin domain protein (myotilin), TTIDLGMD1

Gene Symbol

MYOT

UniProt

Q9UBF9 (Human)

Additional Myotilin Products

Product Documents for Myotilin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Myotilin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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