Highly potent, competitive, preferential dopamine D3
receptor antagonist. Ki
values are 0.52, 5, and 269 nM for human cloned D3
receptors respectively. Centrally active upon systemic administration.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold with the permission of INSERM and BIOPROJET
A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194.
Audinot et al.
Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents.
Sautel et al.
The dopamine D3 receptor antagonist nafadotride inhibits development of locomotor sensitization to amphetamine.
Richtand et al.
Brain Res., 2000;867:239
The citations listed below are publications that use Tocris products. Selected citations for Nafadotride include:
Showing Results 1 - 2 of 2