Catalog Number: 0597
Chemical Name: 4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol hydrochloride
Biological Activity
An α1-adrenoceptor antagonist with only weak antagonism at post-junctional α2 receptors; a potent, persistent antihypertensive and vasodilator.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Alpha-1-adrenoceptor-binding material in rat plasma following single oral administration of naftopidil.
    Borbe and Peter
    Arzneimittelforschung, 1990;40:253
  2. Pharmacological profile of the novel alpha-adrenoceptor antagonist KT-611 (naftopidil).
    Muramatsu et al.
    Jpn.J.Pharmacol., 1991;55:391
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