NEIL1 Antibody

Novus Biologicals | Catalog # NB300-881

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

This NEIL1 Antibody was developed against a peptide with sequence C-DIPSLEPEGTSAS corresponding to C-Terminus according to NP_078884.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for NEIL1 Antibody

Immunohistochemistry-Paraffin: NEIL1 Antibody [NB300-881]

Immunohistochemistry-Paraffin: NEIL1 Antibody [NB300-881]

Immunohistochemistry-Paraffin: NEIL1 Antibody [NB300-881] - Analysis of NEIL1 in paraffin embedded Human Placenta using this antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Human placenta shows strong staining of cytoplasm in syncytiotrophoblasts.

Applications for NEIL1 Antibody

Application
Recommended Usage

Immunohistochemistry

5 - 10 ug/mL

Immunohistochemistry-Paraffin

5 - 10 ug/mL

Peptide ELISA

Detection limit 1:16000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NEIL1

NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002).[supplied by OMIM]

Alternate Names

DNA-(apurinic or apyrimidinic site) lyase Neil1, EC 3.2.2.-, EC 4.2.99.18, endonuclease 8-like 1, endonuclease VIII, Endonuclease VIII-like 1, FLJ22402, FPG1DNA glycosylase/AP lyase Neil1, hFPG1, NEH1, nei endonuclease VIII-like 1 (E. coli), Nei homolog 1, NEI1, Nei-like protein 1

Entrez Gene IDs

79661 (Human)

Gene Symbol

NEIL1

Additional NEIL1 Products

Product Documents for NEIL1 Antibody

Certificate of Analysis

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Product Specific Notices for NEIL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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