Neprilysin/CD10 Antibody (CL12448) - BSA Free

Name: Neprilysin/CD10 Antibody (CL12448) - BSA Free
Brand: Novus Biologicals
SKU: NBP3-15135
Price: 429 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-15135

Submit a review

Product Documents

View Available Conjugates View Available Formulations

100% Guarantee

Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG_2B Clone # CL12448

Format

BSA Free

View all Neprilysin/CD10 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed using a synthetic peptide derived from P08473, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Rat (80%)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2B

Scientific Data Images for Neprilysin/CD10 Antibody (CL12448) - BSA Free

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Staining of human small intestine shows strong apical membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Staining of human kidney shows strong apical membranous positivity in cells in tubules and cells in glomeruli.

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Staining of human pancreas shows very weak positivity in exocrine glandular cells.

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Staining of human skin shows very weak positivity in squamous epithelial cells.

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135]

Immunohistochemistry-Paraffin: Neprilysin/CD10 Antibody (CL12448) [NBP3-15135] - Analysis in human small intestine and pancreas tissues using NBP3-15135 antibody. Corresponding MME RNA-seq data are presented for the same tissues.

View 2 more images

Applications for Neprilysin/CD10 Antibody (CL12448) - BSA Free

Application

Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000

Application Notes

For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Neprilysin/CD10

CD10, also known as the Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, immature B cells with in adult bone marrow and on cells from patients with chronic myelocytic leukemia (CML). CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

Alternate Names

CALLA, CD10, Enkephalinase, Leu-19, MME, Neutral Endopeptidase 24.11, NKH1

Gene Symbol

MME

Additional Neprilysin/CD10 Products

Product Documents for Neprilysin/CD10 Antibody (CL12448) - BSA Free

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Neprilysin/CD10 Antibody (CL12448) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.