Catalog Number: 1908
Biological Activity
Mammalian bombesin-like peptide and endogenous ligand for the neuromedin B receptor (IC50 = 2 nM); first isolated from pig spinal cord. Regulates endocrine and exocrine secretion, smooth muscle contraction, blood pressure, feeding and cell growth.
Technical Data
  • M.Wt:
    1132.3
  • Formula:
    C52H73N15O12S
  • Sequence:
    GNLWATGHFM

    (Modifications: Met-10 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    87096-84-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord.
    Minamino et al.
    Biochem.Biophys.Res.Commun., 1983;114:541
  2. Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor.
    Sainz et al.
    J.Biol.Chem., 1998;273:15927
  3. Neuromedin B.
    Ohki-Hamazaki et al.
    Prog.Neurobiol., 2000;62:297

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