Neuromedin B (porcine)

Catalog # Availability Size / Price Qty
1908/1
Neuromedin B (porcine)
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Description: Mammalian bombesin-like peptide
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Biological Activity

Mammalian bombesin-like peptide and endogenous ligand for the neuromedin B receptor (IC50 = 2 nM); first isolated from pig spinal cord. Regulates endocrine and exocrine secretion, smooth muscle contraction, blood pressure, feeding and cell growth.

Technical Data

M.Wt:
1132.3
Formula:
C52H73N15O12S
Sequence:
GNLWATGHFM

(Modifications: Met-10 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
87096-84-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Neuromedin B.
    Ohki-Hamazaki et al.
    Prog.Neurobiol., 2000;62:297
  2. Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord.
    Minamino et al.
    Biochem.Biophys.Res.Commun., 1983;114:541
  3. Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor.
    Sainz et al.
    J.Biol.Chem., 1998;273:15927

Product Datasheets

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