Biological ActivityNeuromedin B (porcine) is a mammalian bombesin-like peptide and endogenous ligand for the neuromedin B receptor (IC50 = 2 nM); first isolated from pig spinal cord. Regulates endocrine and exocrine secretion, smooth muscle contraction, blood pressure, feeding and cell growth.
(Modifications: Met-10 = C-terminal amide)
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Ohki-Hamazaki et al.
Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord.
Minamino et al.
Four amino acid residues are critical for high affinity binding of neuromedin B to the neuromedin B receptor.
Sainz et al.
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VersaClone cDNA Plasmids
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