Neuromedin U (rat)

Catalog # Availability Size / Price Qty
1917/1
Neuromedin U (rat)
1 Image
Description: Endogenous modulator of blood pressure and flow, gut ion transport, feeding and body temperature
Product Details
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Biological Activity

Endogenous peptide regulating blood pressure, ion transport in the gut, mesenteric blood flow and adrenocortical function. Also decreases food intake and body weight, increases body temperature and heat production, and inhibits gastric acid secretion via the CRH system following central administration in vivo.

Technical Data

Formula:
C124H180N34O31
Sequence:
YKVNEYQGPVAPSGGFFLFRPRN

(Modifications: Asn-23 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
117505-80-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Neuromedin U acts in the cental nervous system to inhibit gastric acid secretion via CRH system.
    Mondal et al.
    Am.J.Physiol.Gastrointest.Liver Physiol., 2003;284:G963
  2. Neuromedin U-8 and U-25: novel uterus stimulating and hypertensive peptides identified in porcine spinal cord.
    Minamino et al.
    Biochem.Biophys.Res.Commun., 1985;130:1078
  3. Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3.
    Szekeres et al.
    J.Biol.Chem., 2000;275:20247

Product Datasheets

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