antagonist; exhibits 520-fold selectivity for P2Y11
receptors. Displays competitive antagonism against ATPγ
values are 6.43 and 7.14 in Ca2+
and cAMP assays respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-γ,γ'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleuk
Meis et al.
The citations listed below are publications that use Tocris products. Selected citations for NF 340 include:
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