GABA uptake inhibitor. IC50
values are 8, 38, 106 and 2370 μ
M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Tiagabine, SK&F 89976-A, CI 966, and NNC-711 are selective for the cloned GABA transporter GAT-1.
Borden et al.
GABA agonists, antagonists and uptake inhibitors. Design and therapeutic aspects.
Krogsgaard-Larsen et al.
Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA binding.
Schousboe et al.
The citations listed below are publications that use Tocris products. Selected citations for (±)-Nipecotic acid include:
Showing Results 1 - 1 of 1