Bioactive metabolite of nociceptin and potent agonist for the ORL1
= 7.9 in mouse vas deferens, Ki
= 0.75 nM for binding to rat forebrain membranes).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Pharmacology of nociceptin and its receptor: a novel therapeutic target.
Calo et al.
Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships.
Varani et al.
The citations listed below are publications that use Tocris products. Selected citations for Nociceptin (1-13)NH2 include:
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