Nociceptin (1-7)
Discontinued Product
1266 has been discontinued.
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Description: Bioactive metabolite of nociceptin
Biological Activity
Nociceptin (1-7) is a bioactive metabolite of nociceptin. Antagonizes nociceptin-induced hyperalgesia, with no effect on nociceptin-induced analgesia.Technical Data
M.Wt:
655.7
Formula:
C31H41N7O9
Sequence:
FGGFTGA
Solubility:
Soluble to 2 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
178249-42-8
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15.
Montiel et al.
J.Neurochem., 1997;68:354 -
Nociceptin (1-7) antagonizes nociceptin-induced hyperalgesia in mice.
Sakurada et al.
Br.J.Pharmacol., 1999;128:941
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