Noggin Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-34141

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Noggin Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Noggin Antibody - BSA Free

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141] - Staining of human prostate shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141] - Staining of human cerebellum shows no positivity in Purkinje cells as expected.
Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141] - Staining of human cerebral cortex shows weak cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141] - Staining of human placenta shows strong cytoplasmic positivity in decidual cells.

Applications for Noggin Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Noggin

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Alternate Names

NOG, SYM1, SYNS1, SYNS1A

Gene Symbol

NOG

UniProt

Q13253

Additional Noggin Products

Product Documents for Noggin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Noggin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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