Endogenous agonist for the GPR55 and CB1
values are 10 and 37 nM respectively) that displays selectivity over CB2
values are 21.2 nM and > 3mM at CB1
respectively). Causes sedation, hypothermia, intestinal immobility and mild antinociception in vivo
. Attenuates sensory neurotransmission in rat mesenteric arteries via GPR55.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Noladin ether, a putative endocannabinoid, attenuates sensory neurotransmission in the rat isolated mesenteric arterial bed via a non-CB1/CB2 Gi/o linked receptor.
Duncan et al.
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor.
Hanus et al.
The orphan receptor GPR55 is a novel cannabinoid receptor.
Ryberg et al.
Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor.
Sugiura et al.
Synthesis and biological activities of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, and its metabolically stable ether-linked analogues.
Suhara et al.
The citations listed below are publications that use Tocris products. Selected citations for Noladin ether include:
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