Noladin ether

Catalog # Availability Size / Price Qty
1411/5
1411/25
Noladin ether | CAS No. 222723-55-9 | Cannabinoid R1/CB1 Agonists
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Description: Endogenous agonist for CB1 and GPR55
Alternative Names: HU 310, 2-Arachidonyl glycerol ether

Chemical Name: 2-[(5Z,8Z,11Z,14Z)-Eicosatetraenyloxy]-1,3-propanediol

Product Details
Citations (1)
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Biological Activity

Endogenous agonist for the GPR55 and CB1 receptors (EC50 values are 10 and 37 nM respectively) that displays selectivity over CB2 receptors (Ki values are 21.2 nM and > 3mM at CB1 and CB2 respectively). Causes sedation, hypothermia, intestinal immobility and mild antinociception in vivo. Attenuates sensory neurotransmission in rat mesenteric arteries via GPR55.

Technical Data

M.Wt:
364.57
Formula:
C23H40O3
Solubility:
Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
Storage:
Desiccate at -20°C
CAS No:
222723-55-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for Noladin ether

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