Catalog Number: 1446
Chemical Name: N-(bis-3-chloro-4-hydroxybenzyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Biological Activity
Inhibitor of anandamide uptake (IC50 = 17.3 μM) with little or no activity at CB1, CB2, TRPV1 and FAAH. Intravenous administration inhibits limb spasticity in mice with chronic relapsing experimental allergic encephalomyelitis (CREAE).
Technical Data
  • M.Wt:
    584.62
  • Formula:
    C34H43Cl2NO3
  • Solubility:
    Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 5mg/ml)
  • Storage:
    Desiccate at -20°C
  • CAS No:
    439080-01-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from VCU-IPF
Background References
  1. A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid.
    Di Marzo et al.
    J.Pharmacol.Exp.Ther., 2002;300:984
  2. New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis.
    Ligresti et al.
    Br.J.Pharmacol., 2006;147:83
  3. Activity of a novel anandamide analog suggests a non-CB1, non-VR1 site of action.
    Griffin et al.
    2001 Symposium on the Cannabinoids, International, 2001;

Have you used O-2093?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information