Oct3/4 inducer. Increases Oct3/4 mRNA levels in HEK293 cells by 2.5- and 4-fold at 10 μ
M and 20 μ
M, respectively. Also increases expression of Oct3/4 in human adult and neonatal fibroblasts.
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Identification of 2-[4-[(4-Methoxyphenyl)methoxy]-phenyl]acetonitrile and derivatives as potent Oct3/4 inducers.
Cheng et al.